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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0243b400b17301129de7d11cb282c72e3057a5f8aaf6a3dd505dfbe49d16c8c5' 
  AND token = 'ynMuOrlMVmzl2I99xR6nekcl/zPtfJwdxfYoAlWzxF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}