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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458bbc1af9b6164fbde5dcf9a23a8c14c0a3bbc989531ed1c144d34e3de6263a' 
  AND token = '6es8JAPclGCue3VtYBEWlCSEh8W3F1jVZzia9wkqnaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}