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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65b977e741a50fe0d5228f8855df315e24ee65755c9813b3507f27fbe0a9914' 
  AND token = '+0Y6ZWb9dP408CCGo9w+TLIeBi83m3i6l4Lg0L70ZY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}