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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86ad89e4f45b0559bf279299b1d067cf71fae7f0462df025d889b40761fd0d29' 
  AND token = 'M01HSJ1hT8Mm2CbKoc3fOSPOy1aPRIo+MG7b58tt4Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}