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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d4679310341c1b0e3b766eceb188d448289f6dc3855794eb2011ea8b185a47' 
  AND token = '+Drz91FZlv3HCpa+6xCqxF96SqjuVxTvbj+N2f2rDBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}