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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38ce9563493479ac1f79e5ae4cf67b5c88fecb13f9f68e075983c17a26236d4' 
  AND token = 'eveo+FsxzRHTcs/zSwV3tgsuuQtzvbss4GvN5VgUwyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}