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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce455eb391ce7c4705678bfdeb5008baf50f47bf2180d697f732a1bdae0cc0f' 
  AND token = 'jN/F/mSq9d7wYecy50+QmdKnmjnIaZvVX31Dk02I4Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}