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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742a6db607cf035ac77a5d95392ec64ece396547d5da17514a662fb9dc433d11' 
  AND token = '81fj0pHz6kQKxvqJ73OHK0zfk8ssYjlA4yOoJNrD/Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}