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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3c3d2c001dfc89b0095058c6d3356131aaffeba596b8a3bfc680b8ba50e755' 
  AND token = 'vaCE3cvEiJB6KsxC3hJXK4NlITACqJxNYNjSOg8e4E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}