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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f515db53c83b0102a15b41096b66d11eb537d675e43dde03c008eee0fcc08b39' 
  AND token = 'eO18c84xNZ7nkfSiilg+safxPPPLFD1Qxw10XBUMs9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}