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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2978ea2bf20be2434678c9063f617a7cccc97476dee3bb8c8e646d83c2f221ba' 
  AND token = '+CcU0puRczaIl73xf/og1DPTHP4I1gUZkrj/tyZ82yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}