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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc7bd22037c065ab31931460b0bb1735ff3c297f42852d10751d033a923d3de' 
  AND token = '2tW4kxcHDf7vQXnimhC5OwogBzt4nN3D8CwJIwB8AkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}