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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4226ea5c4d7974abcea607fe06d4a2f177ee4a365ec8d53d7d04bffa3a9441f3' 
  AND token = 'fqs5+6+F0mk/B8g8IhPz2ZnjNT+ozANjoFBIOpJipaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}