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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca0b9e5f2fe26b2448d4b1f2af29aaf4700a5a332848ad86d18a1880ec192d7d' 
  AND token = 'HYSMtLoKhy9OjLXiKvOTihmhvG4VTG4dFyt0ksIDVaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}