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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1541c931d86a23f68e477a3e171704bd9bf599da2b2864394fec10766aab71' 
  AND token = 'Ut39rU6nD1xYPHoB6mMsuI/tfGHq6CpB8jV9Kwn9Yms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}