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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51eabbd9da866567a7a3deaf0c5ce375ee77a40b25f76f015fd7697a35ac3b9b' 
  AND token = 'LXQ8JOuBQSkDjfxl6D57ECIhdUEPJxF5AXeSkFV80Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}