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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5316d7af802abffed3814700f52b89a6009478c4db8e2edb80ba53dcccad676b' 
  AND token = '1ThlIYsU6wAZ9MHLGfhhtDhfiYgtaDerWLT4G0jWqRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}