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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f7dbbf32aaa0f074b6c44062d352bc359463ec1bae93beeb558f315b89d4678' 
  AND token = 'E0AvLvi0Ln7lqOnpt65l4CsC6TZwLx3L/k04ix30gh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}