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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08b0f242e31078e479b2eef1ad32bfb4abd5f1c8a797f82221bdc53f0f17d7af' 
  AND token = 'ifsyCHF1Fj21lTuDMn4tVI0IUv0sqzO8yiCanmHEvkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}