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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f925f73fbd0a1bc6ff8812f9fec4096bef3365d1ad54c705115000b2fdec1e5' 
  AND token = '4xLn45aLDoLZg5Be0tHDoBQaU04o8lKHpRS2Nll3rgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}