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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f2649eb6c576ae12a72c0e2b5380e893915d2e1f4ee0fa5d9f35a73d41619f' 
  AND token = 'x9dlnNOEc3mohB72A3ZcSAFDnTvKTbiSMc3vFYpDvfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00081

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}