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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c75a91e61d2180e4b82ab93fa10112720e7c5a068b6fa87007572ebeb7469aa7' 
  AND token = 'HKzcxNd9/c9H5sn1g1ppdw7Sqq90sG/7/lpcrHIeAFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}