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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37468730c25f651f2535ec7edc67002e703eda49f592ba907969e8a242e7e44' 
  AND token = '+CMLX2EXYuEZKkhS6+QSrcctlC9l6PjAlaKLk6mYWbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}