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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051456a8f4081ff69b064a6198a816f221fa373f868516285baf4891d0133857' 
  AND token = 'VDrS5hjBu+iqyx9tfPLRt3Rw2O3p2tpQQpwDcsXni70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}