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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb6e5600a23132455795101a166ab56b1f650a8aa79c44e6b9c1655ec512f1ed' 
  AND token = '0eRu1K/yy0+pyNQRu1z5Y4qSm2nX2S7OwM0+nVRIJaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}