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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e19826570ab4b24c4fd702d433946503ba80a0ff126c7c558374e21023e9799b' 
  AND token = 'exD6MHUoxPL3qE2ouC/lIQ8Xu8G6Vt16SGdsacoy6n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}