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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ea4d741041f8fd4a13c072b1e2365908f7ad0976e6e50e2871b3a296c7e106' 
  AND token = 'XJV01pO9djMOVLe3/FpdrRN86IiMMBkcFPvq8edhlk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}