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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd045f2ce909248fa5925f4b434464669a5c345a0e649fb0ba1cc5cce17ce4496' 
  AND token = 'PVRVbFK5jx+vjZmeATZk+6f0tC+LY5oLPuDRoneeXaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}