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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee43687dde373e7c4e610d383415c18340e86da3f424498af9cb339e2619c20' 
  AND token = '0V7S5bineBYDUHbZYGmrs3AQSypGo5yTjirA39wp5SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}