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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ded07ff03152606fe9f7dd15781e8ecb04b293d74414771bfdfe650bd09105e' 
  AND token = 'xLf1x9rf4Xn9Jf977T5/aiwTn0O4HbkliFsL8tpAX2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}