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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751d368ee5d5c3ff74345b448e8203228879dea14353fe6b14c288a617f8c132' 
  AND token = 'MRh+Nxb0y99fJWjRCOO+JmeJUUowxYbOcubQ6CRz+Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}