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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6dcd05e0f1764c2062600ee83c256e6c7b2846e55b45fc89809267ea01ea637' 
  AND token = '+KPakg3Hf6JwXYkGnUO2SBgBUuBTT7rzLk2Poxdj4tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}