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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef80c1a4a740d356074af8fbd92c19d355067ad075ee24b89e7dc05677095bda' 
  AND token = 'znh9jx6BEkLRVtxm2SCE9Km8ivpWAGqVKeRZT8M8OUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}