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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d613ea8bc277645b0b330d7d61efb835126a1922f8816189a1931859646b5d' 
  AND token = 'iPeRS2/ZFodmfO0Gyy2ItonAKljZKzVNqRWxaHPXiiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}