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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bdb70d4d903130696d683c4c1eceb25f458af3b1018ceaf914ae0379769e26' 
  AND token = 'K7vE9UpU4AoWTPHqpmMlJwOB8yuDS0hazbviEn+QM14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}