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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '659cfa006c1b5e03a1e952dd6f0ac5db351ce8108f18d10c9b1558b75353f32b' 
  AND token = '6gucrIvOvFRMYG/ufh8thOoNb2UJbmj2ZaKZ9BeU768=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}