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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a054d7e3ee21179d706b70b34aec55fd5f5b3620b1c2b868c3e06c7ac12414' 
  AND token = '5FsH5sQBgOgr6byiO1J5HX2ja6XGIGWigzrcoGGbtrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}