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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35eddae4e4a243cccd3239196edb503a3b0be509b118e80cec3b4bfbca67785' 
  AND token = '0+yQtUwf/REB8MI/4Rg+KVND9wsTS9p5Xq628eJdiCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}