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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ad1f0c2181a75bb5be450ca43536c3e93a49cb05c9e65aeaef2634b6c9554a' 
  AND token = 'DDDVbhD/SI1a77dE+4uicbNgsY5wRAwx2F1gCzGMcZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}