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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af546758f66a10531740dc434abcf3644a02f1b4f8de048c5d083ca564d2cfe' 
  AND token = 'dqOrbkDjKALTx/tuHfHJbdO+p9YaRSQFm3QKH3o07pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}