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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bdd2a9ac09e40dc7034b800f72e9ae2f42a2b4faa920b282f169af994a5d3d5' 
  AND token = 'A4nWHVVPDkN71b8a/kLFJ1sXwGVtkaDwNT7uuaXWQCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}